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Graft-versus-host disease (GvHD)

Overview

Graft-versus-host disease (GVHD) is a potentially serious complication that can occur after a stem cell or bone marrow transplant, where the transplanted immune cells attack the recipient's tissues and organs. It commonly affects the skin, gastrointestinal tract, and liver, leading to symptoms such as rash, diarrhea, and liver dysfunction. GVHD can range from mild to life-threatening and requires prompt medical intervention, including immunosuppressive therapy, to manage symptoms and prevent further tissue damage.

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