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Hemophilia A, also known as classical hemophilia, is a genetic bleeding disorder caused by insufficient or defective clotting factor VIII, a protein essential for blood coagulation. Individuals with hemophilia A experience prolonged bleeding or spontaneous bleeding episodes, particularly in joints and muscles, which can lead to pain and joint damage over time. Management includes regular infusions of factor VIII concentrates to prevent or treat bleeding episodes, and advances in treatment have significantly improved quality of life and life expectancy for those affected.

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