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Prurigo nodularis is a chronic skin condition characterized by the development of intensely itchy nodules or papules on the skin, often leading to persistent scratching and the formation of crusts or ulcers. It typically presents as multiple raised lesions, which can vary in size and may be distributed across different areas of the body. Prurigo nodularis can significantly impact quality of life due to the severe itching and discomfort experienced by affected individuals, and treatment usually involves a combination of medications to alleviate symptoms and behavioral interventions to prevent further skin damage.

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