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Von Willebrand disease (VWD) is a genetic bleeding disorder characterized by a deficiency or dysfunction of von Willebrand factor (VWF), a protein involved in blood clotting. This deficiency can lead to prolonged bleeding, easy bruising, and excessive bleeding after injury or surgery. Treatment typically involves medications to increase VWF levels or enhance clotting, along with measures to prevent and manage bleeding episodes, such as desmopressin and clotting factor concentrates.

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